Cowling VH (2009) Enhanced mRNA cap
methylation increases Cyclin D1 expression and promotes
cell transformation. Oncogene 2009, in press
Cowling VH (2009) Regulation of mRNA cap
methylation. Biochemical Journal 2009, in press
Fernandez-Sanchez ME, Gonatopoulos-Pournatzis T, Preston G,
Lawlor MA, and Cowling VH (2009)
S-Adenosyl Homocysteine Hydrolase (SAHH) is required for
Myc-induced mRNA cap methylation, protein synthesis and
cell proliferation. Mol Cell Biol 2009, in press
Cole MD and Cowling VH (2009) Specific regulation of mRNA cap methylation
by the c-Myc and E2F1 transcription factors.
Oncogene advance online publication, 12 January 2009;
doi:10.1038/onc.2008.463
Cole MD and Cowling VH (2008) Transcription-independent functions of MYC:
regulation of translation and DNA replication.
Nature Reviews Mol Cel Biol AOP, published online 2008
13 August; doi:10.1038/nrm2467
Cowling VH and Cole MD
(2007) Turning the tables: Myc activates Wnt in
breast cancer. Cell Cycle – 2007 Nov 1 6(21)
Cowling VH and Cole MD (2007) An N-Myc truncation analogous to c-Myc-S
induces cell proliferation independently of
transactivation but dependent on Myc Homology Box
II. Oncogene – 2007 August 20;
doi:10.1038/sj.onc.1210734
Cowling VH, D’Cruz C, Chodosh L and Cole
MD (2007) c-myc transforms human mammary epithelial
cells through repression of DKK1 and SFRP1 and
activation of Wnt signaling. Mol Cell Biol, 2007
Jul;27(14):5135-46
Cowling VH and Cole MD (2007) E-Cadherin repression contributes to c-Myc
induced epithelial cell transformation. Oncogene,
2007 May 24; 26(24) p3582-86. Epub 2006 Dec 4
Cowling VH and Cole MD (2007) HATs Off to Capping: A New Mechanism for
Myc. Cell Cycle, 2007 April 15; 6(8) p307-309
Cowling VH and Cole MD (2007) The Myc Transactivation Domain Promotes
Global Phosphorylation of the RNA pol II
Carboxy-terminal Domain Independently of Direct DNA
Binding. Mol Cell Biol, 2007 March; 27(6)
p2059-2073
Cowling VH and Cole MD (2006) Mechanism of Transcriptional Activation by
the Myc Oncoproteins. Seminars in Cancer Biology
2006 Aug4; 16(4) p242-252
Li H, Cherukuri P, Cowling VH, Cole MD,
Spinella M, Godwin A, Wells W and DiRenzo J (2007) Nestin is expressed in Putative Mammary
Progenitors and is a Selective Marker of Basal
Epithelial Breast Tumors. Cancer Research 2007 Jan
15, 67(2):501-10.
Cowling VH, Chandriani S, Whitfield ML,
and Cole MD (2006) A conserved Myc protein domain, MBIV,
regulates DNA binding, apoptosis and G2 arrest.
Mol Cell Biol 2006 June 6; 11 p4226-4329
Nicke B, Bastien J, Khanna SJ, Warne PH, Beijersbergen RL,
Cowling V, Bernards R, Ganesan TS,
Downward J and Hancock DC (2005) Involvement of MINK, a Ste20 family kinase,
in Ras oncogene-induced growth arrest in human ovarian
surface epithelial cells. Mol Cell. 2005 Dec
9;20(5):673-85
Martins LM, Turk BE, Cowling V, Borg A,
Jarrell ET, Cantley LC, Downward J (2003) Binding specificity and regulation of the
serine protease and PDZ domains of HtrA2/Omi.
J.Biol Chem. 2003 Dec 5;278(49):49417-27
Cowling V and Downward J (2002) Caspase-6 is the direct activator of
caspase-8 in the cytochrome c initiated apoptosis
pathway; absolute requirement for removal of the
prodomain. Cell Death Differ 9(10):1046-1056